II Composition for Prevention or Treatment of Atopic Dermatitis Comprising Skullcapflavone II or Derivatives Thereof
The present invention relates to a composition comprising a derivative of skullcapflavone II represented by Chemical formula 1 for preventing or treating atopic dermatitis. The skullcapflavone II, or an active ingredient of the composition according to the present invention shows an excellent anti-i...
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Main Authors | , , , , , , , , |
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Format | Patent |
Language | English Korean |
Published |
10.02.2023
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to a composition comprising a derivative of skullcapflavone II represented by Chemical formula 1 for preventing or treating atopic dermatitis. The skullcapflavone II, or an active ingredient of the composition according to the present invention shows an excellent anti-inflammatory effect and an itching alleviation effect on atopic dermatitis in in vitro and in vivo experiments, so that the composition can be useful as a preventive or therapeutic agent for atopic dermatitis, which can replace or be used in combination with a conventional therapeutic agent. [Chemical formula 1] In the chemical formula, R_1 to R_4 are the same as defined in the specification.
본 발명은 화학식 1로 표시되는 스컬캅플라본 Ⅱ의 유도체를 함유하는 아토피 피부염의 예방 또는 치료용 조성물에 관한 것이다. 본 발명의 조성물의 유효성분인 스컬캅플라본 Ⅱ는 시험관내 및 생체내 실험에서 아토피 피부염에 대한 뛰어난 염증 억제 효과 및 가려움증 개선 효과를 나타내므로, 종래의 치료제들을 대체하거나 이와 병용이 가능한 아토피 피부염의 예방 또는 치료제로서 유용하게 사용될 수 있다. [화학식 1] JPEGpat00011.jpg4876 상기에서, R1 내지 R4는 명세서에서 정의된 것과 같다. |
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Bibliography: | Application Number: KR20210102105 |