Nucleic acid molecules capable of modulating target gene expression and uses thereof

• Main Authors: KIM YOOSIK, LIM JIN A, PARK HYUNGYU, CHO RYEONGEUN, KU DOYEONG, KIM HANSOL
• Format: Patent
• Language: English; Korean
• Published: 27.12.2022
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

The present application relates to a nucleic acid molecule capable of regulating target gene expression and uses thereof. The nucleic acid molecule according to an embodiment can regulate the expression of a target gene specifically in cells with miRNA capable of binding, and thus can be usefully used as a composition for regulating target gene expression or a pharmaceutical composition for treating diseases. 본 출원은 타겟 유전자 발현을 조절할 수 있는 핵산 분자 및 이의 용도에 관한 것으로, 일 예에 따른 핵산 분자는 결합할 수 있는 miRNA가 존재하는 세포 특이적으로 타겟 유전자의 발현을 조절할 수 있어, 타겟 유전자 발현 조절용 조성물 또는 질환 치료용 약학적 조성물로서 유용하게 활용될 수 있다.