NOVEL TARGET FOR ANTI-CANCER AND IMMUNE-ENHANCING

• Main Authors: CHA MI YOUNG, JEON BU NAM
• Format: Patent
• Language: English; Korean
• Published: 18.10.2022
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; TESTING

The present invention relates to a pharmaceutical composition for treating or preventing cancer, a pharmaceutical composition for enhancing immunity, a method for screening an anticancer agent, and a method for providing information necessary for cancer prognosis analysis. According to the present invention, cancer can be effectively prevented or treated using a CNTN4 inhibitor, and the immunity of an individual can be enhanced. In addition, the present invention is very useful because it can effectively select new anticancer drug candidates by measuring the activity or expression of CNTN4, and can provide information necessary for diagnosing and predicting cancer prognosis. 본 발명은 암 치료 또는 예방용 약학적 조성물, 면역증강용 약학적 조성물, 항암제 스크리닝 방법, 및 암 예후 분석에 필요한 정보를 제공하는 방법에 관한 것이다. 본 발명에 따르면, CNTN4 억제제를 사용하여 암을 효과적으로 예방 또는 치료할 수 있으며, 개체의 면역력을 증강시킬 수 있다. 또한, 본 발명은 CNTN4의 활성 또는 발현 측정을 통해 새로운 항암제 후보물질을 효과적으로 선별할 수 있으며, 암 예후 진단 및 예측에 필요한 정보를 제공할 수 있어 매우 유용하다.