Chlorella sp. Composition for preventing or treating severe acute respiratory syndrome- corona virus infection comprising Chlorella sp. extract or pheophytinized fraction or pyphyrins or carotenones isolated therefrom as active ingredients

• Main Authors: KIM EUN HA, OH WON KEUN, LEE BA WOOL, PONCE ZEA JORGE EDUARDO, KIM SE MI, CHO HYO MOON, CHOI YOUNG KI
• Format: Patent
• Language: English; Korean
• Published: 18.08.2022
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; FISHING; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; FORESTRY; HUMAN NECESSITIES; HUNTING; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES; TRAPPING

The present invention relates to a composition containing a Chlorella sp. extract and a pheophytinized fraction or a porphyrin- or carotenone-based compound isolated therefrom as an active ingredient for prevention or treatment of novel coronavirus infection. The composition has an increased content of porphyrin-based compounds, pheophytin A (compound 1) and pheophytin B (compound 2), which are active compounds, through a chemical method and further contains a carotenone-based compound, so that it can be advantageously used particularly in the treatment and prevention of novel coronavirus infection in humans through the synergistic antiviral activity thereof. 본 발명은 클로렐라(Chlorella sp.)추출물 및 페오피틴화 분획물 또는 이로부터 분리한 폴피린계 또는 카로테논계 화합물을 유효성분으로 포함하는 신종코로나 바이러스 감염의 예방 또는 치료용 조성물에 관한 것으로, 화학적 방법을 통하여 활성화합물인 폴피린계 화합물인 페오피틴 A(화합물 1)과 페오피틴 B(화합물 2)의 함량을 높이고 또한 카로테논계 화합물을 더 포함함으로써 항바이러스 활성의 상승작용을 통하여 특히 사람의 신종코로나 바이러스 감염의 치료와 예방에 유용하게 이용될 수 있다.