Manufacturing method of encapsulated keratin and Cosmetic composition for improving skin barrier with encapsulated keratin manufactured therefrom

• Main Authors: HAN YOUNG HEE, KIM MEE AE, CHOI BYUNG YOUN, PARK YOUNG JAE, CHOI SU JI, SHIN CHAN JAE
• Format: Patent
• Language: English; Korean
• Published: 03.08.2022
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS

The present invention relates to a manufacturing method of encapsulated keratin and a cosmetic composition for improving a skin barrier including the encapsulated keratin prepared by the method. Provided is a cosmetic composition which stabilizes insoluble keratin from cyclodextrins and derivatives thereof, has low cytotoxicity through encapsulation, has excellent anti-inflammatory effect and cell regeneration improvement effect, and exhibits a skin barrier strengthening effect according to the induction of keratinocyte differentiation. The encapsulated keratin is manufactured by mixing purified water, hydroxypropylcyclodextrin, caffeine, polydextrose, hydrolyzed keratin, keratin, maltodextrin, cyclodextrin, asiaticoside, phenoxyethanol, xanthan gum, and hydroxyethylcellulose, and homogenizing the same. 본 발명은 캡슐화케라틴의 제조방법 및 이의 방법으로 제조된 캡술화케라틴을 포함하는 피부장벽 개선용 화장료 조성물에 관한 것으로, 불용성의 케라틴을 사이클로덱스트린 및 그 유도체들로부터 안정화시키고, 캡슐화를 통해 세포독성이 낮고, 항염증효과 및 세포재생 개선 효과가 우수하며, 각질형성세포 분화 유도에 따른 피부 장벽 강화 효과를 발휘하는 화장료 조성물을 제공한다.