사이클로옥타테트라엔 함유 염료 및 조성물

• Main Authors: WU XIAOLIN, ROMANOV NIKOLAI NIKOLAEVICH, ANASTASI CAROLE, LIU XIAOHAI, CALLINGHAM MICHAEL, FRANCAIS ANTOINE, MCCAULEY PATRICK
• Format: Patent
• Language: Korean
• Published: 02.08.2022
• Subjects: ADHESIVES; BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; DERIVATIVES THEREOF; DYES; ENZYMOLOGY; LAKES; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MISCELLANEOUS APPLICATIONS OF MATERIALS; MISCELLANEOUS COMPOSITIONS; MORDANTS; MUTATION OR GENETIC ENGINEERING; NATURAL RESINS; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES; PAINTS; POLISHES; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; SUGARS; VINEGAR; WINE

본 발명의 실시 형태는 사이클로옥타테트라엔(COT) 함유 염료, 및 형광 표지로서의 이의 용도에 관한 것이다. 상기 형광 화합물은 화학식 (I)의 광보호 사이클로옥타테트라엔 모이어티를 포함한다. 사이클로옥타테트라엔(COT)을 함유하는 조성물이 또한 제공된다. 상기 염료 및 조성물은 다양한 생물학적 응용, 예컨대 핵산 서열분석에 사용될 수 있다. [화학식 (I)] JPEGpct00270.jpg2855 Embodiments of the present disclosure relate to cyclooctatetraene containing dyes and their uses as fluorescent labels. Also provided are composition containing cyclooctatetraene. The dyes and compositions may be used in various biological applications, such as nucleic acid sequencing.