Composition containing small molecular weight enzyme hydrolysates of black goat extracts and effective peptide sequence

• Main Authors: JANG AE RA, KIM DONG WOOK, KIM HYE JIN
• Format: Patent
• Language: English; Korean
• Published: 08.07.2022
• Subjects: CHEMISTRY; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

The present invention relates to a composition containing a low molecular weight enzyme hydrolysate of a black goat bone juice obtained by enzymatically hydrolyzing a black goat meat bone juice and an effective peptide isolated from the same. The present invention provides a method for enzymatically hydrolyzing a black goat meat bone juice, obtained by hot water extraction of black goat meat bone, with an optimal enzyme composition to obtain an enzyme hydrolysate, and isolating effective peptides having the amino acid sequences of SEQ ID NOs: 1, 2, and 3 from the enzyme hydrolysate. The black goat meat bone juice hydrolysate and the effective peptides isolated therefrom, obtained as described above, according to the present invention show a high anti-inflammatory effect through inhibition of generation of nitric oxide and prostaglandin E_2, thereby being usefully used as anti-inflammatory functional food, functional cosmetics, or functional medicine for prevention or treatment of inflammatory diseases. 본 발명은 흑염소육골즙으로 효소분해하여 수득한 저분자 흑염소골즙 효소분해물과 이로부터 분리된 유효 펩타이드를 함유하는 조성물에 관한 것이다. 본 발명은 흑염소육골을 열수 추출하여 수득한 흑염소육골즙을 최적의 효소 구성으로 효소분해하여 효소분해물을 수득하고, 이로부터 서열번호 1, 2, 3의 아미노산 서열을 갖는 유효 펩타이드를 분리하는 방법을 제공한다. 상기와 같이 수득한 본 발명의 흑염소육골즙 가수분해물 및 이로부터 분리된 유효 펩타이드는 산화질소 및 프로스타글란딘 E2 생성 억제를 통한 높은 항염 효과를 발휘하여 항염용 기능성 식품, 기능성 화장품이나, 염증성 질환의 예방 또는 치료를 위한 기능성 약품으로 유용하게 사용될 수 있다.