EP2 PHARMACEUTICAL COMPOSITION COMPRISING EP2 ANTAGONIST

The purpose of the present invention is to provide a pharmaceutical composition useful for the prevention and/or treatment of diseases associated with the activation of an EP_2 receptor. A compound represented by general formula (I-A) or a pharmaceutically acceptable salt thereof has a strong antago...

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Bibliographic Details
Main Authors WATANABE AKIO, HIROOKA YASUO, YOSHIDA ATSUSHI, YANG MICHAEL G, LI NING
Format Patent
LanguageEnglish
Korean
Published 01.07.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The purpose of the present invention is to provide a pharmaceutical composition useful for the prevention and/or treatment of diseases associated with the activation of an EP_2 receptor. A compound represented by general formula (I-A) or a pharmaceutically acceptable salt thereof has a strong antagonistic activity against the EP_2 receptor. Accordingly, the pharmaceutical composition containing the compound represented by general formula (IA) or the pharmaceutically acceptable salt thereof can be used as a preventive and/or therapeutic agent for diseases associated with the activation of the EP_2 receptor. In the formula, all symbols have the same meaning as described in the specification. [과제] EP2 수용체의 활성화와 관련된 질환의 예방 및/또는 치료에 유용한 의약 조성물을 제공하는 것. [해결 수단] 하기 일반식 (I-A)로 표시되는 화합물 또는 이의 약학적으로 허용되는 염은 EP2 수용체에 대해 강력한 길항 활성을 갖고, 이에 따라 하기 일반식 (IA)로 표시되는 화합물 또는 이의 약학적으로 허용되는 염을 포함하는 의약 조성물은 EP2 수용체의 활성화와 관련된 질환의 예방 및/또는 치료제로서 사용될 수 있다: JPEGpat00117.jpg2873 (식 중, 모든 기호는 명세서에 기재된 것과 동일한 의미를 갖는다.)
Bibliography:Application Number: KR20210185636