글루코피라노실 유도체 및 이의 용도

• Main Authors: DENG XINSHAN, KANG PANPAN, WANG WEIHUA, WU WUYONG, GU ZHENG, LIU JIANYU
• Format: Patent
• Language: Korean
• Published: 15.03.2022
• Subjects: CHEMISTRY; DERIVATIVES THEREOF; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SUGARS

본 발명은, 나트륨-의존성 글루코스 수송체(SGLT) 억제제로서의 화학식 I의 글루코피라노실 유도체 또는 이의 약학적으로 허용가능한 염 또는 입체 이성질체에 관한 것이며, 또한 상기 유도체를 함유하는 약학 조성물, 및 당뇨병 및 당뇨병-관련 질환 치료용 약물의 제조에서의 상기 화합물 및 상기 약학 조성물의 용도에 관한 것이다. At present relates to a glucopyranosyl derivative and application thereof. In particular, relates to a glucopyranosyl derivative as a sodium-dependent glucose transporters1 (SGLT1) inhibitor, and a pharmaceutically acceptable salt or a stereoisomer thereof, and further relates to a pharmaceutical composition containing the derivative. Further relating to uses of the compound and pharmaceutical composition thereof in the preparation of drugs for the treatment of diabetes and diabetes-related diseases