CD33 표적화 면역요법

• Main Authors: GANO JACOB, TIMMER JOHN C, POGSON MARK, CRAGO WILLIAM, HOLLANDS ANDREW, LEUNG WAI HANG, JONES KYLE, SANABRIA ANGELICA, MA MILTON, ECKELMAN BRENDAN P, JARJOUR JORDAN
• Format: Patent
• Language: Korean
• Published: 11.03.2022
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

본 개시는 암, 감염성 질환, 자가면역 질환, 염증성 질환, 및 면역 결핍증, 또는 이와 관련된 병태의 적어도 하나의 증상을 치료, 예방, 또는 완화시키기 위한 입양 T 세포 요법을 위한 개선된 조성물 및 CD33 표적화 폴리펩티드를 제공한다. The present disclosure provides improved CD33 targeting polypeptides and compositions for adoptive T cell therapies for treating, preventing, or ameliorating at least one symptom of a cancer, infectious disease, autoimmune disease, inflammatory disease, and immunodeficiency, or condition associated therewith.