METHOD FOR PROVIDING INFORMATION FOR CARDIOVASCULAR DISEASE AND KITS USING THE SAME

• Main Authors: LEE JI WON, HONG KYUNG WON, CHOI JA EUN, HWANG TAE SOON
• Format: Patent
• Language: English; Korean
• Published: 08.03.2022
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; VINEGAR; WINE

The present invention provides a method for providing information for hypertension, which comprises the steps of: detecting a single nucleotide polymorphism (SNP) genotype for at least one gene region in between CBX8 and CBX4, between MARCH1 and LINC01207, between RPTOR, CYP1B1 and AS1, between PRDM8, MARCH1 and LINC01207, between UNQ6494 and LOC1019278, between RNF213, GML and CYP11B1, between CNNM2 and RPTOR, and between MYL2, CUX2 and JAG1 from a biological sample separated from an individual; and determining the risk of developing hypertension for the individual based on the detected genotype. 본 명세서에서는 개체로부터 분리된 생물학적 시료로부터 CBX8 및 CBX4 사이, MARCH1 및 LINC01207 사이, RPTOR, CYP1B1 및 AS1 사이, PRDM8 및 MARCH1 및 LINC01207 사이 사이, UNQ6494 및 LOC1019278 사이, RNF213, GML 및 CYP11B1 사이, CNNM2 및 RPTOR 사이, MYL2 및 CUX2 사이 및 JAG1 중 적어도 하나의 유전자 영역에 대한 SNP(single nucleotide polymorphism) 유전자형을 검출하는 단계, 및 검출된 유전자형을 기초로 개체에 대한 고혈압 발병 위험을 결정하는 단계를 포함하는, 고혈압에 대한 정보 제공 방법을 제공한다.