N3pGlu ANTI-N3pGlu AMYLOID BETA PEPTIDE ANTIBODIES AND USES THEREOF

• Main Authors: DEMATTOS RONALD BRADLEY, LU JIRONG, TANG YING
• Format: Patent
• Language: English; Korean
• Published: 28.01.2022
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

인간 N3pGlu Aβ에 대한 항체, 이러한 N3pGlu Aβ 항체를 포함하는 조성물, 및 임상 또는 전임상 알츠하이머병, 다운 증후군, 및 임상 또는 전임상 뇌 아밀로이드 혈관병증을 포함한, Aβ의 침착을 특징으로 하는 질환의 치료를 위한 상기 N3pGlu Aβ 항체의 사용 방법. Antibodies to human N3pGlu Aβ, compositions comprising such N3pGlu Aβ antibodies, and methods of using such N3pGlu Aβ antibodies for the treatment of a disease characterized by deposition of Aβ including clinical or pre-clinical Alzheimer's disease, Down's syndrome, and clinical or pre-clinical cerebral amyloid angiopathy.