7--34--2- 7-AMINO-34-DIHYDROPYRIMIDO PYRIMIDIN-2-ONE DERIVATIVES AS PROTEIN KINASE INHIBITORS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING DISEASE CONTAINING THE SAME
The present invention relates to a 7-amino-3,4-dihydropyrimidopyrimidin-2-one derivative compound exhibiting excellent anti-proliferative efficacy on cancer cells, a pharmaceutically acceptable salt thereof, a hydrate thereof or a stereoisomer thereof, a manufacturing method thereof, a pharmaceutica...
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Main Authors | , , , , , , , , , |
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Format | Patent |
Language | English Korean |
Published |
26.07.2021
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to a 7-amino-3,4-dihydropyrimidopyrimidin-2-one derivative compound exhibiting excellent anti-proliferative efficacy on cancer cells, a pharmaceutically acceptable salt thereof, a hydrate thereof or a stereoisomer thereof, a manufacturing method thereof, a pharmaceutical composition for preventing, alleviating or treating cancer metastasis and proliferative diseases containing the same as an active component, and an anti-cancer composition for cancer cells. The compound exhibits excellent cancer cell inhibitory activity and an anti-proliferative effect, thereby being useful not only for inhibiting cancer cells, but also for preventing cancer metastasis and proliferative diseases or for treating cancer.
본 발명은 암세포에 대한 우수한 항 증식 효능을 나타내는 7-아미노-3,4-디히드로피리미도피리미딘-2-온 유도체 화합물, 이의 약학적으로 허용 가능한 염, 이의 수화물 또는 이의 입체 이성질체와, 이의 제조 방법 및 이를 유효성분으로 함유하는 암 전이 및 증식성 질환의 예방, 경감 또는 치료용 약학 조성물, 및 암세포에 대한 항암 조성물에 관한 것으로서, 상기 화합물은 우수한 암세포 억제 활성 및 항증식 효능을 나타내므로, 암세포 저해는 물론이고 나아가 암 전이 및 증식성 질환의 예방 또는 암 치료에 유용하다. |
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Bibliography: | Application Number: KR20200005305 |