RNA METHOD AND KIT FOR DIAGNOSIS OF DIABETIC NEUROPATHY USING MICRO-RNA

• Main Author: PARK YOUNG KWANG
• Format: Patent
• Language: English; Korean
• Published: 14.07.2021
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; VINEGAR; WINE

Provided is a method for diagnosing diabetic neuropathy. The diagnostic method includes the steps of measuring the miRNA expression level of a diagnostic subject and comparing the measured miRNA expression level with the miRNA expression level of a normal control group, wherein the miRNAs are one or more selected from a first miRNA group consisting of miR-25, miR-23a and miR-142-3p, a second miRNA group consisting of miR-9, miR-29c and miR-134-5p, and a third miRNA group consisting of miR-145 and miR-182. 당뇨병성 신경병증의 진단 방법이 제공된다. 상기 진단 방법은 진단 대상의 miRNA 발현수준을 측정하는 단계 및 상기 측정한 miRNA 발현수준을 정상 대조군의 miRNA 발현수준과 비교하는 단계를 포함하되, 상기 miRNA는, miR-25, miR-23a 및 miR-142-3p로 이루어진 제1 miRNA군, miR-9, miR-29c 및 miR-134-5p로 이루어진 제2 miRNA군 및 miR-145 및 miR-182로 이루어진 제3 miRNA군에서 선택되는 하나 이상인 것을 특징으로 한다.