Composition comprising icaritin and quercetin for preventing or treating nonalcoholic fatty liver disease

• Main Authors: CHUNG A PARK, IL JE CHO, EUN OK KIM, SANG MI PARK, SANG CHAN KIM, JAE KWANG KIM, SOOK JAHR PARK, SUNG HUI BYUN
• Format: Patent
• Language: English; Korean
• Published: 07.07.2021
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

The present invention relates to a composition for preventing or treating liver diseases, comprising icaritin and quercetin. According to the present invention, it is confirmed that a mixed use of icaritin and quercetin shows more excellent effects of protecting hepatic cells than a single use of icaritin or quercetin, and thus an optimal mixing ratio of icaritin and quercetin is derived. In addition, it is confirmed that the composition exhibits a hepatoprotective action and does not induce toxicity to normal cells, thereby having an effect of being used as an active component of a therapeutic agent for liver diseases or a health functional food for protecting liver diseases. 본 발명은 이카리틴 및 퀘르세틴을 포함하는 간질환의 예방 또는 치료용 조성물에 관한 것으로, 본 발명은 이카리틴 및 퀘르세틴을 보함하는 간질환의 예방 또는 치료용 조성물에 관한 것으로, 본 발명의 조성물은 이카리틴 또는 퀘르세틴 단독 사용에 비해 혼합 사용할 경우 간세포보호효과가 우수한 것을 확인하고, 최적배합비를 도출하였으며, 또한 상기 조성물은 간보호작용을 보이며 정상 세포에 독성을 유발하지 않는다는 것을 확인함으로써, 간질환 치료제 또는 간질환 예방을 위한 건강기능성 식품의 유효성분으로 사용할 수 있는 효과가 있다.