Fc GDF15 FUSION POLYPEPTIDE COMPRISING Fc REGION OF IMMUNOGLOBULIN AND GDF15

The present invention relates to: a fusion polypeptide comprising a growth/differentiation factor 15 (GDF15) and an Fc region of immunoglobulin; a pharmaceutical composition comprising the fusion polypeptide; and a method for increasing in vivo duration of the GDF15 comprising a step of fusing the F...

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Bibliographic Details
Main Authors NOH SOOMIN, JUNG SAEM, PARK JI A, HONG JI HO, MIN KYEONGSIK, SON YOUNG DOK, JIN MYUNG WON, NA KYUBONG, KIM YEONCHUL
Format Patent
LanguageEnglish
Korean
Published 30.06.2021
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to: a fusion polypeptide comprising a growth/differentiation factor 15 (GDF15) and an Fc region of immunoglobulin; a pharmaceutical composition comprising the fusion polypeptide; and a method for increasing in vivo duration of the GDF15 comprising a step of fusing the Fc region of the immunoglobulin. GDF15 (Growth/differentiation factor 15) 및 면역글로불린의 Fc 영역을 포함하는 융합 폴리펩타이드, 상기 융합 폴리펩타이드를 포함하는 약학적 조성물, 및 면역글로불린의 Fc 영역을 융합시키는 단계를 포함하는 GDF15의 생체 지속 기간을 증가시키는 방법에 관한 것이다.
Bibliography:Application Number: KR20210082625