Pharmaceutical composition for preventing and treating secondary cancer comprising aldehyde inhibitor and biguanide compounds

• Main Author: KIM HONG YEOUL
• Format: Patent
• Language: English; Korean
• Published: 10.06.2021
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to a pharmaceutical composition for prevention and treatment of secondary cancer, comprising an aldehyde inhibitor and a biguanide-based compound. Secondary cancer refers to cancer which results from the metastasis of cancer starting in one place to a different organ, and exhibits more unfavorable prognosis than the primary cancer. The pharmaceutical composition according to the present invention comprises an aldehyde inhibitor and a biguanide-based compound for prevention and treatment of secondary cancer. By having a more remarkable therapeutic effect specifically on secondary cancer than primary cancer, the pharmaceutical composition of the present invention is expected to be widely used in the treatment of secondary cancer, which is difficult to treat and has an unfavorable prognosis. 본 발명은 알데히드 억제제 및 비구아나이드 계열 화합물을 포함하는 속발성 암의 예방 및 치료용 약학조성물에 관한 것이다. 속발성 암은 다른 부위에서 처음 발생한 암이 전이되어 새로운 장기로 전이한 이차성 암을 의미하는 것으로서, 원발성 암에 비하여 예후가 불량하다. 본 발명에 따른 약학조성물은 알데히드 억제제 및 비구아나이드 계열 화합물을 포함하는 속발성 암의 예방 및 치료용 약학조성물에 관한 것이다. 본 발명의 약학조성물은 원발성 암에 비하여 특이적으로 속발성 암에서 치료 효과가 현저하므로, 치료가 어렵고 예후가 불량한 속발성 암의 치료에 크게 이용될 것으로 기대된다.