인슐린 산생 세포

• Main Authors: HIYOSHI HIDEYUKI, YAMAURA JUNJI, UENO HIKARU, SAKUMA KENSUKE, ITO RYO, YAMAZOE NORIKO, KONAGAYA SHUHEI, TOYODA TARO, MOCHIDA TAISUKE, MATSUMOTO HIROKAZU
• Format: Patent
• Language: Korean
• Published: 26.05.2021
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

본 발명은, 다능성 줄기 세포로부터 내분비 세포를 효율적으로 유도·제조하는 것을 가능하게 하는 새로운 수법을 제공하는 것을 목적으로 한다. 인슐린 양성 또한 NKX6.1 양성의 세포를 30 ％ 이상의 비율로, 또한 인슐린 양성 또한 NKX6.1 음성의 세포를 15 ％ 초과의 비율로 포함하는, 인슐린 산생 세포. The purpose of the present invention is to provide a novel method for making it possible to efficiently induce/produce endocrine cells from pluripotent stem cells. Insulin-producing cells including cells that are insulin-positive and NKX6.1-positive cells in a ratio of at least 30% and cells that are insulin-positive and NKX6.1-negative in a ratio of more than 15%.