화합물

본 발명은 T790M/L858R, T790M/L858R/C797S, L858R, L858R/C797S 내포 EGFR 돌연변이체의 선택적 알로스테릭 저해제인 화합물, 이들의 제조, 이들을 내포하는 제약학적 조성물, 및 치료적으로 활성 물질로서 이들의 용도를 제공한다. The present invention provides compounds which are selective allosteric inhibitors of T790M/L858R, T790M/L858R/C797S, L858R, L858R/C797S containing EGF...

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Bibliographic Details
Main Authors KOCER BUELENT, LAZARSKI KIEL, RICCI ANTONIO, KUHN BERND, NAGEL YVONNE ALICE, OBST SANDER ULRIKE, RUEHER DANIEL, GOERGLER ANNICK, LIANG YANKE, JAESCHKE GEORG, DUPLESSIS MARTIN, STEINER SANDRA
Format Patent
LanguageKorean
Published 09.03.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:본 발명은 T790M/L858R, T790M/L858R/C797S, L858R, L858R/C797S 내포 EGFR 돌연변이체의 선택적 알로스테릭 저해제인 화합물, 이들의 제조, 이들을 내포하는 제약학적 조성물, 및 치료적으로 활성 물질로서 이들의 용도를 제공한다. The present invention provides compounds which are selective allosteric inhibitors of T790M/L858R, T790M/L858R/C797S, L858R, L858R/C797S containing EGFR mutants, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances.
Bibliography:Application Number: KR20207037595