3,4-디클로로-N--5-이소티아졸카르복스아미드의 제조 방법

• Main Authors: SANLI ALI, SCHNATTERER ALBERT, FARIDA TARANEH, LUDWIG JUERGEN, LITTMANN MARTIN, PABST KYRA LARISSA
• Format: Patent
• Language: Korean
• Published: 15.12.2020
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; CHEMISTRY; FISHING; FORESTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HUNTING; METALLURGY; ORGANIC CHEMISTRY; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; TRAPPING

본 발명은 살미생물 및 식물 강화 (숙주 방어 유도인자) 특성을 갖는 3,4-디클로로-N-(2-시아노페닐)-5-이소티아졸카르복스아미드 (이소티아닐)를 제조하고 단리하는 신규한 단일-스테이지 방법에 관한 것이다. 본 발명에 따른 방법에서, 제조 공정으로부터의 폐기물 (예를 들어 용매)의 양은 현저히 감소된다. 생성물은 높은 수율 및 순도 (최소 양의 부산물 및 오염물)로 공급된다. 기존의 제조 방법에 비해, 본 발명에 따른 방법은 낮은 부식성 및 높은 수율 및 높은 선택성의 장점을 갖는다. The present invention relates to a novel, one-stage method for preparing and isolating 3,4-dichloro-N-(2-cyanophenyl)-5-isothiazolecarboxamide (isotianil), which has microbicidal and plant-fortifying (host defence inducer) properties. In the method according to the invention, the amount of waste from the production process (e.g. solvent) is significantly reduced. The product is provided in high yield and purity (minimal amount of by-products and impurities). Compared to existing preparation methods, the method according to the invention has the advantage of low corrosiveness and high yield and high selectivity.