T 세포 제조 조성물 및 방법

• Main Authors: BAKKER NOOR, LENKALA DIVYA REDDY, DEBOER RENATE, VAN BUUREN MARIT M, KOHLER JESSICA, FRITSCH ED, VAN DEN BERG JOOST HUIBERT, SCHUMACHER TON, GOLDSTEIN MATTHEW
• Format: Patent
• Language: Korean
• Published: 22.09.2020
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

제어된 생체외유도 또는 확장에 의한 항원 특이적 T 세포의 생성은 매우 특이적이고 유익한 T 세포 요법을 제공할 수 있다. 본 개시내용은 암 및 다른 병태, 질환 및 장애의 개인맞춤형 항원 특이적 T 세포 요법으로 대상체를 치료하는 데 사용될 수 있는 T 세포 제조 방법 및 치료용 T 세포 조성물을 제공한다. The generation of antigen specific T cells by controlled ex vivo induction or expansion can provide highly specific and beneficial T cell therapies. The present disclosure provides T cell manufacturing methods and therapeutic T cell compositions which can be used for treating subjects with cancer and other conditions, diseases and disorders personal antigen specific T cell therapy.