4-4--1--N-5--3--1H-[34-b]-3- Uses for whitening material of 4-4-methylpiperazin-1-yl-N-5-pyridin-3-yl-1H-pyrazolo[34-b]pyridin-3-ylbenzamide derivatives or pharmaceutical acceptable salt thereof

• Main Authors: JEONG KWAN YOUNG, SON YOU HWA, YOO MIYOUN, PARK CHUL MIN, CHOI SANG UN
• Format: Patent
• Language: English; Korean
• Published: 03.09.2020
• Subjects: CHEMISTRY; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

The present invention relates to uses for a whitening material of a 4-(4-methylpiperazin-1-yl)-N-(5-(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl)benzamide derivative, or a pharmaceutically acceptable salt thereof. A composition for whitening provided in an aspect of the present invention has an excellent effect of inhibiting the promotion of cell melanin even when using a small amount thereof, thereby being able to be usefully used as a beauty product for skin whitening or a product for preventing, alleviating, and treating melanin hyperpigmentation diseases. 4-(4-메틸피페라진-1-일)-N-(5-(피리딘-3-일)-1H-피라졸로[3,4-b]피리딘-3-일)벤즈아미드 유도체, 또는 이의 약학적으로 허용 가능한 염의 미백용 소재 용도에 관한 것으로, 본 발명의 일 측면에서 제공되는 미백용도의 조성물은 적은 양을 사용하여도 세포의 멜라닌 생성 촉진을 억제하는 효과가 우수하므로, 피부 미백용 미용제품, 멜라닌 색소 과다 침착 질환의 예방, 개선 및 치료용 제품으로 유용하게 사용할 수 있다.