인터류킨-17(IL-17)을 사용하여 건병증을 치료하는 방법

• Main Authors: CARTER SHEA, KOLBINGER FRANK, BRUIN GERARD, MCINNES IAIN, WEBER ECKHARD, MILLAR NEAL, SCHIEKER MATTHIAS, MINDEHOLM LINDA
• Format: Patent
• Language: Korean
• Published: 09.07.2020
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

본 발명은 IL-17 길항제, 예를 들어 세쿠키누맙을 사용하여 건병증, 예를 들어 회전근개 건병증을 치료하는 방법에 관한 것이다. 건병증 환자를 치료하기 위한 IL-17 길항제, 예를 들어 IL-17 항체, 예컨대 세쿠키누맙, 및 개시된 용도 및 방법에 사용하기 위한 약제, 투약 섭생, 약학적 제제, 투여형 및 키트가 본원에 또한 개시된다. The present disclosure relates to methods for treating tendinopathy, e.g., rotator cuff tendinopathy, using IL-17 antagonists, e.g., secukinumab. Also disclosed herein are uses of IL-17 antagonists. e.g., IL-17 antibodies, such as secukinumab, for treating tendinopathy patients, as well as medicaments, dosing regimens, pharmaceutical formulations, dosage forms, and kits for use in the disclosed uses and methods.