Novel lactic acid bacteria capable of reducing body weight or body fat and use thereof

• Main Authors: HAN MYUNG JOO, NA KYU HEUM, OH SEONG JUN, KIM DONG HYUN, CHANG HWAN BONG
• Format: Patent
• Language: English; Korean
• Published: 29.06.2020
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; PROCESSES USING MICROORGANISMS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES; VINEGAR; WINE

The present invention provides a novel lactobacillus sp. strain isolated from kimchi. According to the present invention, a specific lactobacillus sp. strain is isolated from kimchi and is highly safe with various functions such as excellent anti-obesity activity, body fat reduction activity, blood sugar control activity, blood sugar-lowering activity, blood cholesterol-lowering activity, blood triglyceride-lowering activity, intestinal microbial endotoxin production inhibitory activity, arteriosclerosis inhibitory activity, anti-inflammatory activity, stress relief activity, anti-anxiety activity, and cognitive function improvement activity, etc. In addition, according to the present invention, a specific lactobacillus sp. strain has excellent thermal stability. Thus, according to the present invention, a specific lactobacillus sp. strain may be used as a material of drug medicines or health functional foods for preventing, ameliorating or treating obesity, diabetes, fatty liver, dyslipidemia, arteriosclerosis, metabolic syndrome, endotoxemia, inflammatory disease, stress, anxiety disorder, cognitive dysfunction, etc. 본 발명은 김치에서 분리된 신규 락토바실러스속 균주를 제공한다. 본 발명에 따른 특정 락토바실러스속 균주는 김치에서 분리되어 안전성이 높고, 우수한 항비만 활성, 체지방 감소 활성, 혈당 조절 활성, 혈당 강하 활성, 혈중 콜레스테롤 저하 활성, 혈중 중성지질 저하 활성, 장내 미생물의 내독소 생산 억제 활성, 동맥경화 억제 활성, 염증 억제 활성, 스트레스 완화 활성, 항불안 활성, 인지기능 개선 활성 등과 같은 다양한 기능성을 갖는다. 또한, 본 발명에 따른 특정 락토바실러스속 균주는 우수한 열안정성을 갖는다. 따라서, 본 발명에 따른 특정 락토바실러스속 균주는 비만, 당뇨병, 지방간, 이상지질혈증, 동맥경화증, 대사증후군, 내독소혈증, 염증 질환, 스트레스, 불안 장애, 인지기능 장애 등을 예방, 개선 또는 치료하기 위한 의약품 또는 건강기능식품의 소재로 사용될 수 있다.