LPS LTA Composition comprising detoxified Lipopolysaccharide and Lipoteichoic acid for preventing or inhibiting formation of biofilm

• Main Authors: LEE KYU HO, KIM JEONG A, JANG BORAM, KANG SEBIN, KWAK HYO SEON, LEE KYUNG JO, JUNG YOUCHUL
• Format: Patent
• Language: English; Korean
• Published: 29.05.2020
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BEER; BIOCHEMISTRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; PROCESSES USING MICROORGANISMS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; TRAPPING; VINEGAR; WINE

The present invention relates to a novel Bacteriodes vulgatus MGM001 strain and to a use thereof. The strain according to the present invention has weaker cytotoxicity of lipopolysaccharide (LPS) compared to existing strains, and has a synergistic effect on bio-film inhibition when used in combination with lipoteichoic acid (LTA). 본원은 신규한 박테리오데스 벌가투스 MGM001 (Bacteriodes vulgatus MGM001) 균주 및 그 용도를 개시한다. 본원에 따른 균주는 LPS의 세포독성이 기존의 균주와 비교하여 약하며, LTA와 조합으로 사용시 생물막 억제에 대한 상승효과를 가진다.