Method for making skin senescent models skin senescent models therefrom and method for screening anti-aging material using the same

• Main Authors: KIM HYOUNG JUNE, SON EUIDONG, HAM MIRA
• Format: Patent
• Language: English; Korean
• Published: 22.05.2020
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PHYSICS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; TESTING; VINEGAR; WINE

The present invention relates to a method for manufacturing a skin aging model which can be used for the study of aging phenomena manufactured by treating dichloroacetate on isolated adipose-derived stem cells, the skin aging model manufactured by the method, and a method for screening anti-aging matter using the skin aging model. By treating dichloroacetate on isolated adipose-derived stem cells, there is an excellent effect of manufacturing the skin aging model in a time and cost-effective manner. 본 발명은 분리된 지방 유래 줄기세포에 디클로로아세테이트를 처리하여 제조된 노화 현상의 연구에 사용할 수 있는 피부 노화 모델을 제조하는 방법, 그 방법에 의해 제조된 피부 노화 모델과, 그 모델을 이용하여 항노화 물질을 스크리닝하는 방법에 관한 것으로, 분리된 지방 유래 줄기세포에 디클로로아세테이트를 처리함으로써 시간 및 비용 효율적으로 피부 노화 모델을 제조할 수 있는 우수한 효과가 있다.