Variola virus diagnostic detection kit using rapid immunochromatography its specific antibody and antibody-producing cell lines

• Main Authors: YI RANG HWANG, MIJUNG JI, BYUNGKI CHO, SEOLHYE HONG, DEOK BUM PARK, GI EUN RHIE, JEONG HOON CHUN
• Format: Patent
• Language: English; Korean
• Published: 04.05.2020
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PHYSICS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; TESTING; VINEGAR; WINE

The present invention relates to a monoclonal antibody specific for smallpox virus, a novel cell line for producing the antibody (1n 299-6, 1n 291-7), and an immunochromatography kit for detection of smallpox virus using the same. The kit exhibits excellent sensitivity to smallpox virus and does not show cross-reactivity to other pathogens and interfering substances. 본 발명은 두창바이러스 특이적인 단일클론 항체, 상기 항체를 생산하는 신규한 세포주(1n 299-6, 1n 291-7), 및 이를 이용한 두창바이러스 탐지용 면역 크로마토그래피 키트에 관한 것이다. 상기 키트는 두창바이러스에 대하여 우수한 민감도를 나타내고 다른 병원체 및 방해물질에 대하여 교차반응을 나타내지 않는다.