Method for preparing liver organoid comprising stem cell derived from liver and use thereof

The present invention relates to a method for producing an organoid comprising liver derived stem cells and a use thereof. The organoid produced by the method activates cytochrome P450, a drug metabolism enzyme in the body, as a model to replace cell and animal experiments, thereby being used as a d...

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Bibliographic Details
Main Authors YOO JONG MAN, HAHN SOO JUNG
Format Patent
LanguageEnglish
Korean
Published 31.03.2020
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PHYSICS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
TESTING
VINEGAR
WINE
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Summary:The present invention relates to a method for producing an organoid comprising liver derived stem cells and a use thereof. The organoid produced by the method activates cytochrome P450, a drug metabolism enzyme in the body, as a model to replace cell and animal experiments, thereby being used as a drug metabolism platform. 간 유래 줄기세포를 포함하는 오가노이드의 제조방법 및 이의 용도에 관한 것으로, 상기 방법에 의해 제조된 오가노이드는 세포 및 동물실험을 대체할 수 있는 모델로서 체내 약물 대사 효소인 시토크롬 P450을 활성화시켰는바 약물대사 플랫폼으로 이용할 수 있다.
Bibliography:Application Number: KR20180114363