NANO HYDROGEL FOR FILLER PROCEDURE WITH IMPROVED BIOCOMPATIBILITY INCLUDING EXOSOME DERIVED FROM STEM CELL CULTURE

• Main Authors: SON, HEE SUN, JEE BO KEUN
• Format: Patent
• Language: English; Korean
• Published: 09.03.2020
• Subjects: AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G; BANDAGES, DRESSINGS OR ABSORBENT PADS; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMISTRY; COMPOSITIONS BASED THEREON; DERIVATIVES THEREOF; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; FILTERS IMPLANTABLE INTO BLOOD VESSELS; FIRST-AID KITS; FOMENTATION; GENERAL PROCESSES OF COMPOUNDING; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; ORGANIC MACROMOLECULAR COMPOUNDS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; POLYSACCHARIDES; PROSTHESES; THEIR PREPARATION OR CHEMICAL WORKING-UP; TREATMENT OR PROTECTION OF EYES OR EARS; USE OF INORGANIC OR NON-MACROMOLECULAR ORGANIC SUBSTANCES ASCOMPOUNDING INGREDIENTS; WORKING-UP

Provided is a nano hydrogel for a filler procedure which can significantly alleviate skin wrinkles. The nano hydrogel is a hydrogel formed of a polymer main chain, a crosslinking agent, and an exosome, wherein the exosome forms a homogeneously distributed three-dimensional network structure, thereby having excellent elasticity and viscosity at a level which can significantly alleviate skin wrinkles. Accordingly, skin wrinkles can be alleviated without a conventional injection type filler procedure using a syringe. 피부 주름을 현저하게 개선할 수 있는 필러 시술용 나노 수화겔이 제공된다. 상기 나노 수화겔은 고분자 주쇄, 가교제 및 엑소좀으로 형성된 수화겔로서, 상기 엑소좀이 균질하게 분포된 3차원 망상 구조를 형성하여, 피부 주름을 현저하게 개선할 수 있는 수준으로 탄성도 및 점도가 우수한 효과가 있다. 이를 통해 종래의 주사기를 이용한 주입식 필러 시술 없이도 피부 주름을 개선할 수 있다.