Pharmaceutical composition for treating multiple sclerosis comprising pracinostat

• Main Authors: LEE SOUNG MIN, SEO SU KIL
• Format: Patent
• Language: English; Korean
• Published: 04.03.2020
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

The present invention relates to a pharmaceutical composition for treating multiple sclerosis containing pracinostat. Pracinostat according to the present invention can selectively induce the expression of immunomodulatory enzyme IDO only in inflammatory lesions in a central nervous system, thereby being able to be usefully used as a novel multiple sclerosis medicine. 본 발명은 프라시노스타트(pracinostat)를 포함하는 다발성 경화증 치료용 약학 조성물에 관한 것이다. 본 발명에 따른 프라시노스타트는 중추신경조직 내 염증병소에서만 선택적으로 면역조절효소 IDO의 발현을 유도하여 염증세포를 제어 할 수 있어 새로운 다발성 경화증 치료제로 유용하게 사용할 수 있다.