새로운 아자퀴놀린 유도체

• Main Authors: ILG THOMAS, KULKE DANIEL, BOEHM CLAUDIA, GRIEBENOW NILS, HALLENBACH WERNER, GOERGENS ULRICH, SCHWARZ HANS GEORG, HEISLER IRING, JANSSEN ISA JANA IRINA, ZHUANG WEI, ALIG BERND, KOEHLER ADELINE, BOERNGEN KIRSTEN, HUEBSCH WALTER
• Format: Patent
• Language: Korean
• Published: 26.02.2020
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

본 발명은 A가 (A1) 또는 (A2)이고, T, R, R, R, R, R, R, 및 Q가 본원에 정의된 바와 같은 화학식 (I)의 아자퀴놀린 화합물, 상기 화합물을 제조하는 방법, 상기 화합물을 제조하는 데 유용한 중간체 화합물, 상기 화합물을 포함하는 제약 조성물 및 조합물, 및 단독 작용제로서 또는 다른 활성 성분과 조합하여 질환, 특히 연충 감염을 치료, 제어 및/또는 예방하기 위한 제약 조성물을 제조하기 위한 상기 화합물의 용도를 포함한다. The present invention covers azaquinoline compounds of general formula (I), with A being (A1) or (A2), and in which T, R1, R2, R3, R4, R5, R6 and Q are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment, control and/or prevention of diseases, in particular of helminth infections, as a sole agent or in combination with other active ingredients.