Method for Measuring Concentration of Fibrinogen in Blood Sample and Nanoparticles for the Same

• Main Authors: LEE DONG TAK, LEE GYU DO, KWON DO HYUNG, KIM IN SU, YOON DAE SUNG, LEE GYU BOK, LEE SANG WON
• Format: Patent
• Language: English; Korean
• Published: 25.10.2019
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

The present invention relates to a method for measuring fibrinogen concentration in a blood sample, the method enabling the measuring of the concentration of a fibrinogen protein present in a blood sample from a human body. By using the method for measuring fibrinogen concentration, according to the present invention, an enzyme is not used, and thus convenient usage is achieved, and an error due to a factor affecting in-vivo enzyme activity does not occur. In addition, since a reference plasma is not measured, the measuring time is reduced, and convenience is achieved, and thus, by having excellent accuracy, precision and reproducibility compared to conventional techniques, the method may be usefully employed for measuring fibrinogen concentration in a blood sample. 본 발명은 인체의 혈액 샘플 내 존재하는 피브리노겐(fibrinogen) 단백질의 농도를 측정할 수 있는 혈액 샘플 내 피브리노겐 농도 측정 방법에 관한 것으로, 본 발명의 피브리노겐 농도 측정 방법을 이용하면, 효소를 사용하지 않기 때문에 사용이 편리하고, 생체 내 효소의 활성에 영향을 주는 인자로 인한 오차가 발생하지 않으며, 레퍼런스 플라즈마의 측정이 없기 때문에 측정 시간이 감소하며 편리하므로, 종래의 기술에 비해 정확도, 정밀도 및 재현성이 우수하여, 혈액 샘플 내 피브리노겐 농도를 측정하는데 유용하게 사용될 수 있다.