ANTIBODIES AGAINST FCRN AND USE THEREOF

본 발명에서는 특히, FcRn에 결합하는 단백질, 예를 들면, 높은 친화성 (affinity)과 선택성 (selectivity)으로 FcRn을 저해하는 면역글로불린을 제시한다. 이들 FcRn-결합 단백질은 자가면역 질환을 비롯한 다양한 질환을 치료하는데 이용될 수 있다. This disclosure provides,inter alia,proteins that bind to FcRn,e.g.,immunoglobulins that inhibit FcRn with high affinity and selectivity. The FcRn-b...

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Main Authors LIU LIMING, TENHOOR CHRISTOPHER, LADNER ROBERT CHARLES, DUMONT JENNIFER, MURUGANANDAM ARUMUGAM, BITONTI ALAN J, STATTEL JAMES, SATO AARON, WOOD CLIVE, MCDONNELL KEVIN
Format Patent
LanguageEnglish
Korean
Published 09.09.2019
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:본 발명에서는 특히, FcRn에 결합하는 단백질, 예를 들면, 높은 친화성 (affinity)과 선택성 (selectivity)으로 FcRn을 저해하는 면역글로불린을 제시한다. 이들 FcRn-결합 단백질은 자가면역 질환을 비롯한 다양한 질환을 치료하는데 이용될 수 있다. This disclosure provides,inter alia,proteins that bind to FcRn,e.g.,immunoglobulins that inhibit FcRn with high affinity and selectivity. The FcRn-binding proteins can be used to treat a variety of disorders including autoimmune disorders.
Bibliography:Application Number: KR20197025353