MALT1 억제제로서의 피라졸 유도체

• Main Authors: KREUTTER KEVIN D, EDWARDS JAMES PATRICK, BERTHELOT DIDIER JEAN CLAUDE, SHEN FANG, ALLISON BRETT DOUGLAS, THURING JOHANNES WILHELMUS JOHN FITZGERALD, WU TONGFEI, PHILIPPAR ULRIKE, BARBAY JOSEPH KENT, CONNOLLY PETER J, DIELS GASTON, LU TIANBAO, CUMMINGS MAXWELL DAVID
• Format: Patent
• Language: Korean
• Published: 09.08.2019
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

MALT1의 조절에 의해 영향을 받는 질환, 증후군, 상태 및 장애를 치료하기 위한 화합물, 조성물 및 방법이 개시된다. 이러한 화합물은 화학식 (I)으로 나타낸다:(I) 상기 식에서, R, R,R, R, R, R, R, G및 G는 본 명세서 및 청구범위에 정의된 바와 같다. Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the modulation of MALT1. Such compounds are represented by Formula (I) as follows:wherein R1, R2, R3, R4, R5, R6, R5, G1, and G2 are defined herein.