Drygel sheet controlling the release of specific component and having swelling and shrinkage characteristics and method for preparing thereof

The present invention relates to a drygel sheet controlling the release of a specific component and having swelling and shrinkage characteristics, and a preparation method thereof. After a water-soluble polymer is dissolved in water to form a hydrogel having a three-dimensional network structure and...

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Bibliographic Details
Main Authors LEE HWAN MYUNG, SEO DONG SUNG, KIM YOON SOO, JO NAK SEOK
Format Patent
LanguageEnglish
Korean
Published 04.07.2019
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Summary:The present invention relates to a drygel sheet controlling the release of a specific component and having swelling and shrinkage characteristics, and a preparation method thereof. After a water-soluble polymer is dissolved in water to form a hydrogel having a three-dimensional network structure and contains a composition including a specific component as a carrier for which a specific hydrophobic component having physiological activity is to be a stable composition, moisture in the hydrogel is removed and the three-dimensional network structure is more densely bound. Accordingly, provided is a drygel sheet in which the composition including the specific hydrophobic component having physiological activity is fixed in the three-dimensional network structure in which water is removed. 본 발명은 특정 성분의 방출 제어와 팽윤 및 수축 특성을 함께 갖는 드라이겔 시트 및 이의 제조방법에 관한 것으로, 보다 상세하게는, 생리활성이 있는 특정의 소수성 성분이 안정한 조성물로 존재하기 위한 지지체로 수용성 고분자를 물에 용해하여 3차원 그물구조를 갖는 하이드로겔을 만들어 특정 성분이 포함된 조성물을 함유시킨 후, 그 하이드로겔 속에 포함되어 있는 수분을 제거하여 3차원 그물구조를 더욱 촘촘하게 결속시킴으로써 생리활성이 있는 특정의 소수성 성분이 포함된 조성물이 물이 빠져나간 겔의 3차원 그물구조 속에 고정되는 드라이겔 시트를 제공하는 효과가 있다.
Bibliography:Application Number: KR20170180168