Intermediates of chiral piperidine derivatives and preparation method thereof
By a manufacturing method of the present invention, it is possible to manufacture tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate having optical activity at a high yield while having high purity and optical activity by a method capable of industrially mass production by using commercially availabl...
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Format | Patent |
Language | English Korean |
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19.06.2019
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Abstract | By a manufacturing method of the present invention, it is possible to manufacture tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate having optical activity at a high yield while having high purity and optical activity by a method capable of industrially mass production by using commercially available reagents and solvents. In addition, by using a novel intermediate of the present invention, it is possible to manufacture tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate having optical activity in a high purity and the high yield.
본 발명의 제조방법을 통하여 광학활성을 갖는 터트-부틸 3-메틸-4-옥소피페리딘-1-카르복실레이트를 통상적으로 사용 가능한 시약과 용매를 사용하여, 산업적으로 대량생산이 가능한 방법으로 고순도의 광학활성을 가지면서 고수율로 제조할 수 있다. 또한, 본 발명의 신규 중간체를 통하여 광학활성을 갖는 터트-부틸 3-메틸-4-옥소피페리딘-1-카르복실레이트를 고순도 및 고수율로 제조할 수 있다. |
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AbstractList | By a manufacturing method of the present invention, it is possible to manufacture tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate having optical activity at a high yield while having high purity and optical activity by a method capable of industrially mass production by using commercially available reagents and solvents. In addition, by using a novel intermediate of the present invention, it is possible to manufacture tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate having optical activity in a high purity and the high yield.
본 발명의 제조방법을 통하여 광학활성을 갖는 터트-부틸 3-메틸-4-옥소피페리딘-1-카르복실레이트를 통상적으로 사용 가능한 시약과 용매를 사용하여, 산업적으로 대량생산이 가능한 방법으로 고순도의 광학활성을 가지면서 고수율로 제조할 수 있다. 또한, 본 발명의 신규 중간체를 통하여 광학활성을 갖는 터트-부틸 3-메틸-4-옥소피페리딘-1-카르복실레이트를 고순도 및 고수율로 제조할 수 있다. |
Author | KO DONG HYUN RYU CHAE YOUNG HEO SEUNGPYEONG LEE HYUK WOO KIM EUN SUN KWEON JAE HONG CHOI KWANG DO |
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DocumentTitleAlternate | 광학활성을 갖는 피페리딘 유도체의 중간체 및 이의 제조방법 |
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Snippet | By a manufacturing method of the present invention, it is possible to manufacture tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate having optical activity at... |
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Title | Intermediates of chiral piperidine derivatives and preparation method thereof |
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