ODAM Odontogenic Ameloblast-Associated protein DNA DNA aptamer binding to ODAMOdontogenic Ameloblast-Associated protein with specificity and Uses thereof

• Main Authors: LEE BANG HYUN, GU MAN BOCK
• Format: Patent
• Language: English; Korean
• Published: 14.06.2019
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PHYSICS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; TESTING; VINEGAR; WINE

The present invention relates to a nucleic acid aptamer binding specifically to odontogenic ameloblast-associated protein (ODAM) and a use thereof. According to the present invention, a nucleic acid aptamer for detecting ODAM, and a method, a composition, a sensor, and a kit for detecting ODAM, each comprising the same aptamer, are useful for detecting ODAM present in a sample on the basis of the high specificity and affinity to the ODAM aptamer for ODAM. 본 발명은 오담(ODAM, Odontogenic Ameloblast-Associated protein)에 특이적으로 결합하는 핵산 앱타머 및 그 용도에 관한 것이다. 본 발명에 따르면 오담 검출용 핵산 앱타머, 이를 포함하는 오담의 검출방법, 검출용 조성물, 검출용 센서 및 검출용 키트는 오담 앱타머의 오담에 대한 높은 특이성과 결합력을 바탕으로 시료 내 존재하는 오담의 검출에 유용하다.