Pharmaceutical composition for anti-inflammatory and improvement of bone tissue generation or cartilage tissue generation comprising purified fraction materials from Stauntonia hexaphylla leaves or flavonoid compounds and caffeic acid compounds separated therefrom as active ingredients

• Main Authors: LEE, DONG GU, KIM, SAE ROM, LEE, YONG NAM, KANG, HU WON, LEE, GYU OK, PAN, SANG O, CHOI, CHUL YUNG, YOO, JI SEOK, KIM, JAE YONG, KIM, JAE GAP
• Format: Patent
• Language: English; Korean
• Published: 13.05.2019
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

The present invention relates to: a manufacturing method of a Stauntonia hexaphylla leaf-derived extract or a fractional purified product; the Stauntonia hexaphylla leaf-derived extract or the fractional purified product manufactured by the manufacturing method; and a pharmaceutical composition for anti-inflammation, or promotion of bone tissue formation or cartilage tissue formation, which contains at least one selected from a group consisting of the Stauntonia hexaphylla leaf-derived extract or the fractional purified product, a caffeic acid compound, and a novel flavonoid compound separated from the extract or the fractional purified product as an active component. 본 발명은 멀꿀(Stauntonia hexaphylla) 잎 유래 추출물 또는 분획 정제물의 제조방법, 상기 제조방법으로 제조한 멀꿀 잎 유래 추출물 또는 분획 정제물, 및 상기 멀꿀 잎 유래 추출물 또는 분획 정제물, 또는 상기 추출물 또는 분획 정제물에서 분리된 카페인산 화합물 및 신규 플라보노이드 화합물로 이루어진 군에서 선택된 1이상을 포함하는 것을 유효성분으로 포함하는, 항염, 또는 골조직 생성 또는 연골조직 생성 촉진용 약학적 조성물에 관한 것이다.