TGF-βRI 억제제인 벤조트리아졸에서 유도된 α,β-불포화 아미드계 화합물

본 발명은 TGF-βR1 억제제의 구조가 식(I)으로 표시되는 벤조트리아졸에 의해 유도된 α,β-불포화 아미드계 화합물 또는 이의 약학적으로 허용 가능한 염을 공개한다. A benzotriazole-derived ± and ²-unsaturated amide compound used as TGF-²R1 inhibitor or a pharmaceutically acceptable salt thereof, the structure of the compound being as shown in formula (I)....

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Bibliographic Details
Main Authors SUN FEI, CHEN SHUHUI, LU JIANYU, HU GUOPING, LI JIAN, WU LIFANG, DING CHARLES Z
Format Patent
LanguageKorean
Published 20.02.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:본 발명은 TGF-βR1 억제제의 구조가 식(I)으로 표시되는 벤조트리아졸에 의해 유도된 α,β-불포화 아미드계 화합물 또는 이의 약학적으로 허용 가능한 염을 공개한다. A benzotriazole-derived ± and ²-unsaturated amide compound used as TGF-²R1 inhibitor or a pharmaceutically acceptable salt thereof, the structure of the compound being as shown in formula (I).
Bibliography:Application Number: KR20197001025