Composition for preventing improving or treating of fibrosis
The present invention relates to a composition comprising a Phaseolus angularis extract, a fraction thereof or oleanolin acid acetate isolated therefrom as an active ingredient. The composition has an effect of inhibiting epithelial-mesenchymal transition, increasing pulmonary volume reduced by pulm...
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Main Authors | , , , , , |
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Format | Patent |
Language | English Korean |
Published |
09.01.2019
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to a composition comprising a Phaseolus angularis extract, a fraction thereof or oleanolin acid acetate isolated therefrom as an active ingredient. The composition has an effect of inhibiting epithelial-mesenchymal transition, increasing pulmonary volume reduced by pulmonary fibrosis, and ameliorating liver fibrosis and oxidative stress, and thus can be useful for preventing, ameliorating, or treating fibrosis.
본 발명은 적소두 추출물, 이의 분획물 또는 이로부터 분리한 올레아놀린산 아세테이트를 유효성분으로 포함하는 조성물에 관한 것으로, 상기 조성물은 상피-간엽 이행을 억제하고, 폐섬유화에 의하여 감소된 폐용적을 증가시키며, 간섬유화 및 산화적 스트레스를 개선하는 효능이 있으므로 섬유화증의 예방, 개선 또는 치료 용도로 유용하게 이용될 수 있다. |
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Bibliography: | Application Number: KR20180031003 |