Salts of amide derivatives and method for preparing the same

In the present invention, a cyclised amino acid is disclosed as an aliphatic or aromatic disulfonate or lactam structure, which is a salt of an amide derivative represented by chemical formula 1. The salt of the amide derivative does not absorb moisture, and is stable and has excellent solubility in...

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Main Authors HAN, GA RAM, JUNG, KI WON, HAN HAIZHU, KIM, HYEON JEONG, LEE, IN KYU, KIM, A REUM, CHUNG, IN HWA, AN, JI HUN, SHIN, JAE WON, MO, KIL WOONG
Format Patent
LanguageEnglish
Korean
Published 28.12.2018
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:In the present invention, a cyclised amino acid is disclosed as an aliphatic or aromatic disulfonate or lactam structure, which is a salt of an amide derivative represented by chemical formula 1. The salt of the amide derivative does not absorb moisture, and is stable and has excellent solubility in water. In chemical formula 1, the B ring is a substituted or unsubstituted heteroaryl group, X is a bond, hydroxy, lower alkylene, lower alkenylene, carbonyl or -NH-, and A is lower alkylene or -lower alkylene-O-. 본 명세서에는 하기 화학식1의 아미드 유도체의 염으로서, [화학식 1]지방족 또는 방향족의 다이설포네이트 또는 락탐 구조로 환형화된 아미노산(cyclised amino acid)염이 개시된다. 상기 아미드 유도체의 염은 수분을 흡습하지 않아 안정하면서도 물에 대한 용해도가 우수하다.
Bibliography:Application Number: KR20170078132