c-Met A novel anti c-Met antibody and use thereof

The present invention relates to a novel antibody or an antigen-binding fragment thereof specifically binding to a human liver cell growth factor receptor (c-Met), and to a composition for preventing or treating cancer comprising the same, wherein the antibody can exhibit excellent cancer cell proli...

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Bibliographic Details
Main Authors LEE KYUNG WOO, MOON SEUNG KEE, JEON EUN JU, CHOI EUN SU, AN KI YOUNG
Format Patent
LanguageEnglish
Korean
Published 10.12.2018
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
TESTING
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Summary:The present invention relates to a novel antibody or an antigen-binding fragment thereof specifically binding to a human liver cell growth factor receptor (c-Met), and to a composition for preventing or treating cancer comprising the same, wherein the antibody can exhibit excellent cancer cell proliferation inhibitory activity and remarkably excellent anticancer activity with a small amount, so that cancer can be effectively prevented or treated. 본 발명은 인간 간 세포 성장 인자 수용체 (c-Met)에 특이적으로 결합하는 신규 항체 또는 그의 항원 결합 단편, 및 이를 포함하는 암의 예방 또는 치료용 조성물에 관한 것으로, 상기 항체는 적은 양으로도 우수한 암 세포 증식 저해 활성 및 현저히 우수한 항암활성을 나타내어 암을 효과적으로 예방 또는 치료할 수 있다.
Bibliography:Application Number: KR20180061888