색소성망막염의 치료

본 발명은 색소성망막염 GTPase 조절인자 ORF15 아이소형(RPGR)을 인코딩하는 뉴클레오티드 서열을 포함하는 폴리뉴클레오티드에 관한 것으로, RPGR-인코딩 뉴클레오티드 서열은 서열의 복제 정확도를 증가시키기 위해 코돈 최적화되었다. A polynucleotide comprising a nucleotide sequence encoding the retinitis pigmentosa GTPase regulator ORF15 isoform (RPGRORF15), wherein the RPGRORF15-encoding nucleo...

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Bibliographic Details
Main Authors FISCHER DOMINIK, MACLAREN ROBERT
Format Patent
LanguageKorean
Published 27.04.2018
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:본 발명은 색소성망막염 GTPase 조절인자 ORF15 아이소형(RPGR)을 인코딩하는 뉴클레오티드 서열을 포함하는 폴리뉴클레오티드에 관한 것으로, RPGR-인코딩 뉴클레오티드 서열은 서열의 복제 정확도를 증가시키기 위해 코돈 최적화되었다. A polynucleotide comprising a nucleotide sequence encoding the retinitis pigmentosa GTPase regulator ORF15 isoform (RPGRORF15), wherein the RPGRORF15-encoding nucleotide sequence has been codon optimised to increase fidelity of replication of the sequence.
Bibliography:Application Number: KR20187009860