Method for mass production of sesquiterpene from Polyporus brumalis

The present invention relates to a method for mass-producing sesquiterpene at high yields. To this end, Polyporellus brumalis is cultured in a magnesium-containing medium in an attempt to increase expression rate of a gene encoding sesquiterpene synthase, a gene encoding farnesyl diphosphate synthas...

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Bibliographic Details
Main Authors LEE, SU YEON, LEE, SUNG SUK, KIM, MYUNG KIL, RYU, SUN HWA
Format Patent
LanguageEnglish
Korean
Published 07.03.2018
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The present invention relates to a method for mass-producing sesquiterpene at high yields. To this end, Polyporellus brumalis is cultured in a magnesium-containing medium in an attempt to increase expression rate of a gene encoding sesquiterpene synthase, a gene encoding farnesyl diphosphate synthase, and a gene encoding isopentenyl diphosphate isomerase. 본 발명은 마그네슘을 포함하는 배지에서 겨울우산버섯을 배양하여, 이소펜테닐2인산 이성화효소(isopentenyl diphosphate isomerase)를 코딩하는 유전자, 파르네실 2인산 합성효소(farnesyl diphosphate synthase)를 코딩하는 유전자 및 세스퀴테르펜 합성효소(sesquiterpene synthase)를 코딩하는 유전자의 발현량을 증대시킴으로써, 세스퀴테르펜을 고수율로 대량 생산할 수 있는 방법에 관한 것이다.
Bibliography:Application Number: KR20160108148