DNA NOVEL POLYMERS AND DNA COPOLYMER COATINGS

• Main Authors: DINGWALL ANNE CECILE, BROWN ANDREW A, RICHEZ ALEXANDRE, VON HATTEN XAVIER, GEORGE WAYNE N
• Format: Patent
• Language: English; Korean
• Published: 01.09.2017
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMBINATORIAL CHEMISTRY; COMPOSITIONS BASED THEREON; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES; MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; ORGANIC MACROMOLECULAR COMPOUNDS; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; THEIR PREPARATION OR CHEMICAL WORKING-UP; VINEGAR; WINE

본원에 기재된 일부 구체예는 표면 기능화를 위한 신규한 폴리머 코팅 및 DNA 서열화 및 다른 진단 적용에서 사용하기 위한 기재의 표면(들)에 사전-그라프팅된 DNA-코폴리머를 그라프팅하는 신규한 공정에 관한 것이다. The present invention relates to A polymer for surface functionalization, comprising a recurring unit of Formula (V):Wherein each R1d and R2d is independently selected from hydrogen, optionally substituted alkyl or optionally substituted phenyl;each R3d is selected from hydrogen, optionally substituted alkyl, optionally substituted phenyl, or optionally substituted C7-14 aralkyl;RB is selected from azido, optionally substituted amino, Boc-protected amino, hydroxy, thiol, alkynyl, alkenyl, halo, epoxy, tetrazine or aldehyde;each L4 and L5 is independently selected from an optionally substituted alkylene linker or an optionally substituted heteroalkylene linker. The invention also relates to a substrate comprising said polymer.