ASK1 SOLID FORMS OF AN ASK1 INHIBITOR

5-(4-시클로프로필-1H-이미다졸-1-일)-N-(6-(4-이소프로필-4H-1,2,4-트리아졸-3-일)피리딘-2-일)-2-플루오로-4-메틸벤즈아미드 (화합물 I)의 결정질 형태를 제조하고, 고체 상태로 특징화하였다. 상기 결정질 형태의 제조 방법 및 사용 방법이 또한 제공된다. Crystalline forms of 5-(4-cyclopropyl-1H-imidazol-1-yl)-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-2-fluoro-4-methylbenzamide (Compou...

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Main Authors LATHROP STEPHEN P, ANDRES MARK, CARRA ERNEST A, LAPINA OLGA VIKTOROVNA, YU LOK HIM, CHAN BRENDA J. BURKE, CHIU ANNA, SMOLENSKAYA VALERIYA, NOTTE GREGORY
Format Patent
LanguageEnglish
Korean
Published 23.08.2017
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:5-(4-시클로프로필-1H-이미다졸-1-일)-N-(6-(4-이소프로필-4H-1,2,4-트리아졸-3-일)피리딘-2-일)-2-플루오로-4-메틸벤즈아미드 (화합물 I)의 결정질 형태를 제조하고, 고체 상태로 특징화하였다. 상기 결정질 형태의 제조 방법 및 사용 방법이 또한 제공된다. Crystalline forms of 5-(4-cyclopropyl-1H-imidazol-1-yl)-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-2-fluoro-4-methylbenzamide (Compound I) were prepared and characterized in the solid state:Also provided are processes of manufacture and methods of using the crystalline forms.
Bibliography:Application Number: KR20177020152