6--16-- COMBINATION OF A 6-OXO-16-DIHYDRO-PYRIDAZINE DERIVATIVE HAVING ANTI-CANCER ACTIVITY WITH AN EGFR INHIBITOR

N-[3-[[2-[4-(4-아세틸피페라진-1-일)-2-메톡시-아닐리노]-5-(트리플루오로메틸)피리미딘-4-일]아미노]페닐]프로프-2-엔아미드와 조합된, 3-(1-{3-[5-(1-메틸-피페리딘-4-일메톡시)-피리미딘-2-일]-벤질}-6-옥소-1,6-디히드로-피리다진-3-일)-벤조니트릴 또는 이의 약학적으로 허용 가능한 염 및/또는 용매화물의 약학적 조성물. A pharmaceutical composition of 3-(1-{3-[5-(1-Methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-...

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Bibliographic Details
Main Authors BLADT FRIEDHELM, FRIESE HAMIM MANJA
Format Patent
LanguageEnglish
Korean
Published 07.08.2017
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:N-[3-[[2-[4-(4-아세틸피페라진-1-일)-2-메톡시-아닐리노]-5-(트리플루오로메틸)피리미딘-4-일]아미노]페닐]프로프-2-엔아미드와 조합된, 3-(1-{3-[5-(1-메틸-피페리딘-4-일메톡시)-피리미딘-2-일]-벤질}-6-옥소-1,6-디히드로-피리다진-3-일)-벤조니트릴 또는 이의 약학적으로 허용 가능한 염 및/또는 용매화물의 약학적 조성물. A pharmaceutical composition of 3-(1-{3-[5-(1-Methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile or a pharmaceutically acceptable salt and/or solvate thereof in combination with N-[3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide.
Bibliography:Application Number: KR20177018885