4S-4-4--2--5--28--14--16--3- METHOD FOR THE PREPARATION OF 4S-4-4-CYANO-2-METHOXYPHENYL-5-ETHOXY-28-DIMETHYL-14-DIHYDRO-16-NAPHTHYRIDINE-3-CARBOX-AMIDE AND THE PURIFICATION THEREOF FOR USE AS AN ACTIVE PHARMACEUTICAL INGREDIENT

본 발명은 화학식 I의 (4S)-4-(4-시아노-2-메톡시페닐)-5-에톡시-2,8-디메틸-1,4-디히드로-1,6-나프티리딘-3-카르복스아미드의 신규하고 개선된 제조 방법 및 화학식 I의 (4S)-4-(4-시아노-2-메톡시페닐)-5-에톡시-2,8-디메틸-1,4-디히드로-1,6-나프티리딘-3-카르복스아미드의 결정질 변형체 I의 제조 및 용도에 관한 것이다. <화학식 I> The present invention relates to a novel and improved process for preparing (4S)-4-(4-c...

Full description

Saved in:
Bibliographic Details
Main Authors GRUNENBERG ALFONS, GARKE GUNNAR, PLATZEK JOHANNES
Format Patent
LanguageEnglish
Korean
Published 12.04.2017
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:본 발명은 화학식 I의 (4S)-4-(4-시아노-2-메톡시페닐)-5-에톡시-2,8-디메틸-1,4-디히드로-1,6-나프티리딘-3-카르복스아미드의 신규하고 개선된 제조 방법 및 화학식 I의 (4S)-4-(4-시아노-2-메톡시페닐)-5-에톡시-2,8-디메틸-1,4-디히드로-1,6-나프티리딘-3-카르복스아미드의 결정질 변형체 I의 제조 및 용도에 관한 것이다. <화학식 I> The present invention relates to a novel and improved process for preparing (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide of the formula (I)and also the preparation and use of the crystalline polymorph I of (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide of the formula (I).
Bibliography:Application Number: KR20177005278