REAGENTS SET FOR DIAGNOSING OVARIAN CANCER AND METHOD FOR DIAGNOSING OVARIAN CANCER BY USING THE SAME
The purpose of the present invention is to provide a biomarker which has enhanced sensitivity and specificity for the diagnosis of ovarian cancer. The present invention relates to a technique for measuring a biomarker to diagnose ovarian cancer and analyze properties thereof, for analyzing the bioma...
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Main Authors | , , , |
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Format | Patent |
Language | English Korean |
Published |
08.11.2016
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Subjects | |
Online Access | Get full text |
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Summary: | The purpose of the present invention is to provide a biomarker which has enhanced sensitivity and specificity for the diagnosis of ovarian cancer. The present invention relates to a technique for measuring a biomarker to diagnose ovarian cancer and analyze properties thereof, for analyzing the biomarker, and for predicting ovarian cancer. More specifically, the present invention relates to a reagent set for the diagnosis of ovarian cancer, which is used to measure the levels of at least three multi-biomarkers in a sample; to a kit for the diagnosis of ovarian cancer, which includes the reagent set; and to a method for diagnosing the probability of ovarian cancer in an object by using the reagent set. The multi-biomarkers are selected from the following biomarker panels: (i) human epididymis protein 4 (HE4); (ii) carcinoembryonic antigen (CEA); (iii) creatinine; and (iv) transthyretin (TTR), wherein a combination of HE4, creatinine, and TTR is excluded. In addition, the present invention relates to a computer analysis system or software which is used to analyze or predict the presence of ovarian cancer cells on the basis of the levels of the multi-biomarkers.
본 발명은 난소암 진단과 특성분석을 위한 바이오마커의 측정, 분석 및 예측 기술에 관한 것으로, 보다 상세하게는, 시료 중의 하기 바이오마커 패널중에서 선택되는 3개 이상의 다중 바이오마커의 레벨을 측정하기 위한 난소암 진단용 시약 세트; 상기 시약 세트를 포함하는 난소암 진단용 키트; 및 상기 시약 세트를 이용하여 대상의 난소암의 가능성을 진단하는 방법에 관한 것이다: (ⅰ) HE4(human epididymis protein 4, 인간 부고환 단백질 4); (ⅱ) CEA(carcinoembryonic antigen, 암태아성 단백질 항원); (ⅲ) 크레아티닌(creatinine); 및 (ⅳ) TTR(transthyretin, 트랜스타이레틴), 단, HE4, 크레아티닌 및 TTR의 조합은 제외한다. 또한, 본 발명은 상기 다중 바이오마커의 레벨에 기초하여 난소암의 존재를 분석 또는 예측하는데 사용되는 컴퓨터 분석 시스템 또는 소프트웨어에 관한 것이다. |
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Bibliography: | Application Number: KR20150060669 |