IMPROVED ACETYL-COA CARBOXYLASE VARIANTS

본 발명은 지방산 유도체를 포함하는 말로닐-CoA 유래 화합물의 생성을 위해 아세틸-CoA 카르복실라아제(ACC) 변이체들 및 이들을 발현시키는 숙주 세포들에 관한 것이다. 또한, 증가된 양의 말로닐-CoA 유래 화합물들 및 관련 세포 배양물들을 생성하는 방법들이 고려된다. The disclosure relates to acetyl-CoA carboxylase (ACC) variants and host cells expressing them for the production of malonyl-CoA derived compounds...

Full description

Saved in:
Bibliographic Details
Main Authors WINGER JESSICA, CHANG CINDY, BEHROUZIAN BEHNAZ, GREENFIELD DEREK L, TRIMBUR DONALD E, SCHIRMER ANDREAS W
Format Patent
LanguageEnglish
Korean
Published 04.05.2016
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
Online AccessGet full text

Cover

More Information
Summary:본 발명은 지방산 유도체를 포함하는 말로닐-CoA 유래 화합물의 생성을 위해 아세틸-CoA 카르복실라아제(ACC) 변이체들 및 이들을 발현시키는 숙주 세포들에 관한 것이다. 또한, 증가된 양의 말로닐-CoA 유래 화합물들 및 관련 세포 배양물들을 생성하는 방법들이 고려된다. The disclosure relates to acetyl-CoA carboxylase (ACC) variants and host cells expressing them for the production of malonyl-CoA derived compounds including fatty acid derivatives. Further contemplated are methods of producing increased amounts of malonyl-CoA derived compounds and related cell cultures.
Bibliography:Application Number: KR20167009710